Anti-VEGFA Polyclonal Antibody-抗体-抗体-生物在线

Anti-VEGFA Polyclonal Antibody

商家询价

产品名称： Anti-VEGFA Polyclonal Antibody

英文名称： Anti-VEGFA Polyclonal Antibody

产品编号： K001655P

产品价格： null

产品产地：北京

品牌商标： solarbio

更新时间： 2025-01-17T10:18:30

使用范围： WB IF IP

北京索莱宝科技有限公司

联系人 : 索莱宝-龚思雨
地址 : 北京市通州区中关村科技园区通州园金桥科技产业基地景盛南四街15号85A三层
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产品详情

Anti-VEGFA Polyclonal Antibody
品牌：solarbio | 货号：K001655P
商品货号： 商品品牌： 规格 基本售价： 选择规格
K001655P-50ul solarbio 50ul 960.00元 
K001655P-100ul solarbio 100ul 1600.00元

商品货号：	商品品牌：	规格	基本售价：	选择规格
K001655P-50ul	solarbio	50ul	960.00元
K001655P-100ul	solarbio	100ul	1600.00元

英文名称 Anti-VEGFA Polyclonal Antibody
别名 MVCD1;VEGF;VPF
应用 WB IF IP
稀释比例 WB 1:500-2000. IF 1:50-200. IP 1:50-100.
交叉反应 Human Mouse Rat
蛋白分子量 27kDa
Gene ID 7422
保存 Store at -20°C. Avoid freeze / thaw cycles.
储存液 Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
纯化方法 Affinity purification
亚型 IgG
免疫原 A synthetic peptide of human VEGFA
性状 液体
Public Immunogen Range A synthetic peptide of human VEGFA
Subcellular Locations Secreted
Swiss Prot P15692
克隆类型 Polyclonal Antibody
背景资料 This gene is a member of the PDGF/VEGF growth factor family. It encodes a heparin-binding protein, which exists as a disulfide-linked homodimer. This growth factor induces proliferation and migration of vascular endothelial cells, and is essential for both physiological and pathological angiogenesis. Disruption of this gene in mice resulted in abnormal embryonic blood vessel formation. This gene is upregulated in many known tumors and its expression is correlated with tumor stage and progression. Elevated levels of this protein are found in patients with POEMS syndrome, also known as Crow-Fukase syndrome. Allelic variants of this gene have been associated with microvascular complications of diabetes 1 (MVCD1) and atherosclerosis. Alternatively spliced transcript variants encoding different isoforms have been described. There is also evidence for alternative translation initiation from upstream non-AUG (CUG) codons resulting in additional isoforms. A recent study showed that a C-terminally extended isoform is produced by use of an alternative in-frame translation termination codon via a stop codon readthrough mechanism, and that this isoform is antiangiogenic. Expression of some isoforms derived from the AUG start codon is regulated by a small upstream open reading frame, which is located within an internal ribosome entry site.

英文名称	Anti-VEGFA Polyclonal Antibody
别名	MVCD1;VEGF;VPF
应用	WB IF IP
稀释比例	WB 1:500-2000. IF 1:50-200. IP 1:50-100.
交叉反应	Human Mouse Rat
蛋白分子量	27kDa
Gene ID	7422
保存	Store at -20°C. Avoid freeze / thaw cycles.
储存液	Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
纯化方法	Affinity purification
亚型	IgG
免疫原	A synthetic peptide of human VEGFA
性状	液体
Public Immunogen Range	A synthetic peptide of human VEGFA
Subcellular Locations	Secreted
Swiss Prot	P15692
克隆类型	Polyclonal Antibody
背景资料	This gene is a member of the PDGF/VEGF growth factor family. It encodes a heparin-binding protein, which exists as a disulfide-linked homodimer. This growth factor induces proliferation and migration of vascular endothelial cells, and is essential for both physiological and pathological angiogenesis. Disruption of this gene in mice resulted in abnormal embryonic blood vessel formation. This gene is upregulated in many known tumors and its expression is correlated with tumor stage and progression. Elevated levels of this protein are found in patients with POEMS syndrome, also known as Crow-Fukase syndrome. Allelic variants of this gene have been associated with microvascular complications of diabetes 1 (MVCD1) and atherosclerosis. Alternatively spliced transcript variants encoding different isoforms have been described. There is also evidence for alternative translation initiation from upstream non-AUG (CUG) codons resulting in additional isoforms. A recent study showed that a C-terminally extended isoform is produced by use of an alternative in-frame translation termination codon via a stop codon readthrough mechanism, and that this isoform is antiangiogenic. Expression of some isoforms derived from the AUG start codon is regulated by a small upstream open reading frame, which is located within an internal ribosome entry site.